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Magic™ Antibody Discovery - Human HVEM / TNFRSF14 (39-202) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0216F)

Datasheet
This membrane protein is Human HVEM / TNFRSF14 (39-202). It has been tested in SDS-PAGE, ELISA, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HVEM / TNFRSF14
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 43.5 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 39 - Val 202 (Accession # NP_003811.2).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • HVEM / TNFRSF14
  • Full Name
  • TNF receptor superfamily member 14
  • Introduction
  • This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; tumor necrosis factor receptor superfamily member 14; CD40-like protein; herpes virus entry mediator A; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); tumor necrosis factor receptor-like gene2

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