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Magic™ Antibody Discovery - Human IFN-alpha / beta R2 (27-243) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0330F)

Datasheet
This membrane protein is Human IFN-alpha / beta R2 (27-243). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IFN-alpha / beta R2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 51.4 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ile 27 - Lys 243 (Accession # P48551-2).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IFN-alpha / beta R2
  • Full Name
  • interferon alpha and beta receptor subunit 2
  • Introduction
  • The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.
  • Alternative Names
  • IFN-R; IMD45; IFNABR; IFNARB; IFN-alpha-REC; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; human interferon alpha/beta receptor; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2

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