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Magic™ Antibody Discovery - Human IL-2 (21-153) Membrane Protein, Partial, -His -Avi tag, [Biotin] (CAT#: MP0373F)

Datasheet
This membrane protein is Human IL-2 (21-153). It has been tested in SDS-PAGE, ELISA, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 19.1 kDa. The protein migrates as 19 kDa and 20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 21 - Thr 153 (Accession # P60568-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus, followed by an Avi tag.
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS with Arginine, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

Target

  • Target Protein
  • IL-2
  • Full Name
  • interleukin 2
  • Introduction
  • This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
  • Alternative Names
  • IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; aldesleukin; in regulation of T-cell clonal expansion

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