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Magic™ Antibody Discovery - Human IL-27 Ra / TCCR (33-514) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0386F)

Datasheet
This membrane protein is Human IL-27 Ra / TCCR (33-514). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-27 Ra / TCCR
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 78.9 kDa. The protein migrates as 100-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 33 - Arg 514 (Accession # AAH28003).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-27 Ra / TCCR
  • Full Name
  • interleukin 27 receptor subunit alpha
  • Introduction
  • In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
  • Alternative Names
  • CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; T-cell cytokine receptor type 1; class I cytokine receptor; cytokine receptor WSX-1; cytokine receptor-like 1; interleukin 27 receptor, alpha; type I T-cell cytokine receptor

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