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Magic™ Antibody Discovery - Human LOXL2 (26-774) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0570F)

Datasheet
This membrane protein is Human LOXL2 (26-774). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LOXL2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 111.6 kDa. As a result of Glycosylation, the protein migrates as 120-130 kDa under reducing (R) condition, and 200-240 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Gln 26 - Gln 774 (Accession # NP_002309).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >75% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • LOXL2
  • Full Name
  • lysyl oxidase like 2
  • Introduction
  • This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
  • Alternative Names
  • LOR; LOR2; WS9-14; lysyl oxidase homolog 2; lysyl oxidase related 2; lysyl oxidase-like 2 delta e13; lysyl oxidase-like 2 protein; lysyl oxidase-like protein 2; lysyl oxidase-related protein 2; lysyl oxidase-related protein WS9-14

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