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Magic™ Antibody Discovery - Human MAG / Siglec-4a (20-516) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0643F)

Datasheet
This membrane protein is Human MAG / Siglec-4a (20-516). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MAG / Siglec-4a
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 81.1 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gly 20 - Pro 516 (Accession # P20916-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • MAG / Siglec-4a
  • Full Name
  • myelin associated glycoprotein
  • Introduction
  • The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
  • Alternative Names
  • GMA; S-MAG; SPG75; SIGLEC4A; SIGLEC-4A; myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A

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