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Magic™ Antibody Discovery - Human MIS RII (18-144) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0641F)

Datasheet
This membrane protein is Human MIS RII (18-144). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MIS RII
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 40.0 kDa.
  • Sequence
  • AA Pro 18 - Ser 144 (Accession # Q16671-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • MIS RII
  • Full Name
  • anti-Mullerian hormone receptor type 2
  • Introduction
  • This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • AMHR; MRII; MISR2; MISRII; anti-Muellerian hormone type-2 receptor; AMH type II receptor; MIS type II receptor; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor; anti-Muellerian hormone type II receptor; anti-Mullerian hormone receptor, type II

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