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Magic™ Antibody Discovery - Human MMP-1 (20-469) Membrane Protein, Partial, -His tag (CAT#: MP0633F)

Datasheet
This membrane protein is Human MMP-1 (20-469). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MMP-1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 53.1 kDa. The protein migrates as 57-64 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Phe 20 - Asn 469 (Accession # NP_002412.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 20 mM MES, 150 mM NaCl, pH6.0. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

Target

  • Target Protein
  • MMP-1
  • Full Name
  • matrix metallopeptidase 1
  • Introduction
  • This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
  • Alternative Names
  • CLG; CLGN; interstitial collagenase; fibroblast collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1

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