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Magic™ Antibody Discovery - Human NKp30 / NCR3 / CD337 (19-135) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0679F)

Datasheet
This membrane protein is Human NKp30 / NCR3 / CD337 (19-135). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NKp30 / NCR3 / CD337
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 39.5 kDa. The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 19 - Gly 135 (Accession # AAH52582).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • NKp30 / NCR3 / CD337
  • Full Name
  • natural cytotoxicity triggering receptor 3
  • Introduction
  • The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • 1C7; MALS; CD337; LY117; NKp30; natural cytotoxicity triggering receptor 3; NK-p30; activating NK-A1 receptor; activating natural killer receptor p30; lymphocyte antigen 117; natural killer cell p30-related protein

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