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Magic™ Antibody Discovery - Human P-Selectin / CD62P (42-771) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0791F)

Datasheet
This membrane protein is Human P-Selectin / CD62P (41-171). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P-Selectin / CD62P
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 106.6 kDa. The protein migrates as 146-160 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
  • Sequence
  • AA Trp 42 - Ala 771 (Accession # AAN06828).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • P-Selectin / CD62P
  • Full Name
  • selectin P
  • Introduction
  • This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
  • Alternative Names
  • CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM; P-selectin; CD62 antigen-like family member P; GMP-140; granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; selectin P (granule membrane protein 140kDa, antigen CD62)

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