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Magic™ Antibody Discovery - Human PD-L2 / B7-DC Membrane Protein, Partial, -mIgG1 Fc tag (CAT#: MP1472F)

Datasheet
This membrane protein is Human PD-L2 / B7-DC (20-219). It has been tested in SDS-PGAE, ELISA, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PD-L2 / B7-DC
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 48.9 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 20 - Pro 219 (Accession # AAI13679)

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PGAE, ELISA, FACS
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, (pH7.5). Trehalose is added as protectant before lyophilization.

    Please contact us for customized formulation or product form if needed.

Target

  • Target Protein
  • PD-L2 / B7-DC
  • Full Name
  • programmed cell death 1 ligand 2
  • Introduction
  • This gene is nvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (which is evaluated by similarity).
  • Alternative Names
  • B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7-DC; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2

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