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Magic™ Antibody Discovery - Human TIGIT (22-141) Membrane Protein, Partial, -mIgG2a Fc tag (CAT#: MP0480F)

Datasheet
This membrane protein is Human TIGIT (22-141). It has been tested in SDS-PAGE, ELISA, BLI, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TIGIT
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 40.1 kDa. The protein migrates as 42-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Met 22 - Pro 141 (Accession # Q495A1-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI, FACS
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by reduced SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • TIGIT
  • Full Name
  • T cell immunoreceptor with Ig and ITIM domains
  • Introduction
  • This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses
  • Alternative Names
  • VSIG9; VSTM3; WUCAM; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9, VSTM3; Washington University cell adhesion molecule

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