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Magic™ Antibody Discovery - Human TIMP-2 (27-220) Membrane Protein, Partial, -His tag (CAT#: MP0453F)

Datasheet
This membrane protein is Human TIMP-2 (27-220). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TIMP-2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 22.6 kDa. The protein migrates as 23-26 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Cys 27 - Pro 220 (Accession # NP_003246.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • TIMP-2
  • Full Name
  • TIMP metallopeptidase inhibitor 2
  • Introduction
  • This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
  • Alternative Names
  • DDC8; CSC-21K; metalloproteinase inhibitor 2; testicular secretory protein Li 57; tissue inhibitor of metalloproteinases 2

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