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Magic™ Antibody Discovery - Mouse 4-1BB / TNFRSF9 (24-211) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0903F)

Datasheet
This membrane protein is Mouse 4-1BB / TNFRSF9 (24-211). It has been tested in SDS-PAGE, ELISA, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • 4-1BB / TNFRSF9
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 46.7 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Val 24 - Leu 211 (Accession # Q8R037-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • 4-1BB / TNFRSF9
  • Full Name
  • tumor necrosis factor receptor superfamily, member 9
  • Introduction
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
  • Alternative Names
  • ILA; Ly6; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik; tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CD137 antigen; T-cell antigen 4-1BB; secreted CD137 antigen

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