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Magic™ Antibody Discovery - Mouse BAFF / TNFSF13B / CD257 (127-309) Membrane Protein, Partial, mIgG2a Fc- tag, low endotoxin (CAT#: MP0976F)

Datasheet
This membrane protein is Mouse BAFF / TNFSF13B / CD257 (127-309). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • BAFF / TNFSF13B / CD257
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 47.7 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 127 - Leu 309 (Accession # Q9WU72-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • BAFF / TNFSF13B / CD257
  • Full Name
  • tumor necrosis factor (ligand) superfamily, member 13b
  • Introduction
  • Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
  • Alternative Names
  • BL; BAF; TAL; BAFF; BLyS; zTNF; TALL1; THANK; zTNF4; TALL-1; Tnlg7a; TNFSF20; D8Ertd387; D8Ertd387e; tumor necrosis factor ligand superfamily member 13B; b cell-activating factor; tumor necrosis factor ligand 7a

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