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Magic™ Antibody Discovery - Mouse Fc gamma RIIB/CD32b (40-217) Membrane Protein, Partial, -His tag (CAT#: MP1418F)

Datasheet
This membrane protein is Mouse Fc gamma RIIB/CD32b (40-217). It has been tested in SDS-PAGE, SPR, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • Fc gamma RIIB/CD32b
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 22.2 kDa. The protein migrates as 32-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Thr 40 - Arg 217 (Accession # NP_001070657.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SPR, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His Tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Fc gamma RIIB/CD32b
  • Full Name
  • Fc receptor, IgG, low affinity IIb
  • Introduction
  • The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • Fcg; CD32; Fcgr; Fcr-; Ly-1; LyM-; Fc[g]; Fcgr2; Fcr-2; Fcr-3; Ly-17; Ly-m2; LyM-1; Lym-1; fcRII; FcgRII; Fcgamm; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik; low affinity immunoglobulin gamma Fc region; receptor II-b; Fc gamma RIIB; Fc-gamma-RII; FcgammaRIIB; fc gamma receptor IIB; fc-gamma RII; fc-gamma-RIIB; igG Fc receptor II beta; low affinity immunoglobulin gamma Fc region receptor II; lymphocyte antigen 17

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