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Magic™ Membrane Protein Biotinylated Human CLDN6 (Claudin 6) Expressed in HEK293, Full Length (CAT#: MPX0563K)

Datasheet
This product is a 24.5 kDa Biotinylated Human CLDN6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN6
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 24.5 kDa
  • TMD
  • 4
  • Sequence
  • MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGL
    WMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLA
    GAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNP
    LVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARY
    STSAPAISRGPSEYPTKNYV

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • Tag free
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • > 95% as determined by SEC-HPLC
  • Buffer
  • Supplied as 0.22um filtered solution in PBS, pH 7.4

Target

  • Target Protein
  • CLDN6
  • Full Name
  • Claudin 6
  • Introduction
  • Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
  • Alternative Names
  • CLDN6; claudin-6; skullin; Claudin 6

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