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Magic™ Membrane Protein Human ABCC1 (ATP binding cassette subfamily C member 1) Expressed in E.coli with 6xHis tag at the N-terminus for Antibody Discovery, Partial (1248-1531aa) (CAT#: MPX4277K)

Datasheet
This product is a 35.9 kDa Human ABCC1 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCC1
  • Protein Length
  • Partial (1248-1531aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 35.9 kDa
  • TMD
  • 17
  • Sequence
  • VRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAkDaGLV

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • ABCC1
  • Full Name
  • ATP binding cassette subfamily C member 1
  • Introduction
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
  • Alternative Names
  • MRP; ABCC; GS-X; MRP1; ABC29; DFNA77; multidrug resistance-associated protein 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant; ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; LTC4 transporter; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; ABCC1; ATP binding cassette subfamily C member 1

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