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Magic™ Membrane Protein Human ABCC12 (ATP binding cassette subfamily C member 12) Full Length (CAT#: MPC1602K) Made to Order

Datasheet
This product is a 152.2 kDa Human ABCC12 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCC12
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 152.2 kDa
  • TMD
  • 10
  • Sequence
  • MVGEGPYLISDLDQRGRRRSFAERYDPSLKTMIPVRPCARLAPNPVDDAG
    LLSFATFSWLTPVMVKGYRQRLTVDTLPPLSTYDSSDTNAKRFRVLWDEE
    VARVGPEKASLSHVVWKFQRTRVLMDIVANILCIIMAAIGPVILIHQILQ
    QTERTSGKVWVGIGLCIALFATEFTKVFFWALAWAINYRTAIRLKVALST
    LVFENLVSFKTLTHISVGEVLNILSSDSYSLFEAALFCPLPATIPILMVF
    CAAYAFFILGPTALIGISVYVIFIPVQMFMAKLNSAFRRSAILVTDKRVQ
    TMNEFLTCIRLIKMYAWEKSFTNTIQDIRRRERKLLEKAGFVQSGNSALA
    PIVSTIAIVLTLSCHILLRRKLTAPVAFSVIAMFNVMKFSIAILPFSIKA
    MAEANVSLRRMKKILIDKSPPSYITQPEDPDTVLLLANATLTWEHEASRK
    STPKKLQNQKRHLCKKQRSEAYSERSPPAKGATGPEEQSDSLKSVLHSIS
    FVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGTLAYVSQQA
    WIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERG
    LNLSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTL
    RGKTVVLVTHQLQFLESCDEVILLEDGEICEKGTHKELMEERGRYAKLIH
    NLRGLQFKDPEHLYNAAMVEAFKESPAEREEDAGIIVLAPGNEKDEGKES
    ETGSEFVDTKVPEHQLIQTESPQEGTVTWKTYHTYIKASGGYLLSLFTVF
    LFLLMIGSAAFSNWWLGLWLDKGSRMTCGPQGNRTMCEVGAVLADIGQHV
    YQWVYTASMVFMLVFGVTKGFVFTKTTLMASSSLHDTVFDKILKSPMSFF
    DTTPTGRLMNRFSKDMDELDVRLPFHAENFLQQFFMVVFILVILAAVFPA
    VLLVVASLAVGFFILLRIFHRGVQELKKVENVSRSPWFTHITSSMQGLGI
    IHAYGKKESCITYHLLYFNCALRWFALRMDVLMNILTFTVALLVTLSFSS
    ISTSSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSVELLREYISTCVPE
    CTHPLKVGTCPKDWPSRGEITFRDYQMRYRDNTPLVLDSLNLNIQSGQTV
    GIVGRTGSGKSSLGMALFRLVEPASGTIFIDEVDICILSLEDLRTKLTVI
    PQDPVLFVGTVRYNLDPFESHTDEMLWQVLERTFMRDTIMKLPEKLQAEV
    TENGENFSVGERQLLCVARALLRNSKIILLDEATASMDSKTDTLVQNTIK
    DAFKGCTVLTIAHRLNTVLNCDHVLVMENGKVIEFDKPEVLAEKPDSAFA
    MLLAAEVRL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCC12
  • Full Name
  • ATP binding cassette subfamily C member 12
  • Introduction
  • This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
  • Alternative Names
  • ABCC12; MRP9; ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; multidrug resistance-associated protein 9; ATP binding cassette subfamily C member 12

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