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Magic™ Membrane Protein Human ADAM12 (ADAM metallopeptidase domain 12) Expressed in CHO for Antibody Discovery, Partial (29-513aa) (CAT#: MPX0427K)

Datasheet
This product is a 55 kDa Human ADAM12 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADAM12
  • Protein Length
  • Partial (29-513aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 55 kDa
  • TMD
  • 1
  • Sequence
  • RGVSLWNQGRADEVVSASVGSG
    DLWIPVKSFDSKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYL
    QDGTDVSLARNYTVILGHCYYHGHVRGYSDSAVSLSTCSGLRGLIVFENE
    SYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHHNTPNLAAKNVFPPPSQT
    WARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDK
    FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
    DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAH
    ELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDL
    ETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRC
    CNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSSNSCDLPEFCTGASP
    HCPANVYLHDGHS

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Sodium Acetate, CaCl2 and NaCl.

Target

  • Target Protein
  • ADAM12
  • Full Name
  • ADAM metallopeptidase domain 12
  • Introduction
  • This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.
  • Alternative Names
  • ADAM12; MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alpha; metalloprotease-disintegrin 12 transmembrane; ADAM metallopeptidase domain 12

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