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Magic™ Membrane Protein Human ADAM8 (ADAM metallopeptidase domain 8) Expressed in NS0 for Antibody Discovery, Partial (1-497aa) (CAT#: MPX0731K)

Datasheet
This product is a 38 kDa Human ADAM8 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADAM8
  • Protein Length
  • Partial (1-497aa)
  • Protein Class
  • Protease
  • Molecular Weight
  • 38 kDa
  • TMD
  • 1
  • Sequence
  • MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHL
    GLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPR
    GQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGG
    RHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETR
    YVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLE
    IWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTT
    VGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQG
    CRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAP
    DLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAH
    GTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTP

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Glycerol, Tris, NaCl and CaCl2.

Target

  • Target Protein
  • ADAM8
  • Full Name
  • ADAM metallopeptidase domain 8
  • Introduction
  • This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ADAM8; MS2; CD156; CD156a; disintegrin and metalloproteinase domain-containing protein 8; a disintegrin and metalloproteinase domain 8; cell surface antigen MS2; human leukocyte differentiation antigen; ADAM metallopeptidase domain 8

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