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Magic™ Membrane Protein Human ADGRE2 (Adhesion G protein-coupled receptor E2) Expressed in CHO for Antibody Discovery, Partial (24-478aa) (CAT#: MPX0020K)

Datasheet
This product is a 50.5 kDa Human ADGRE2 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRE2
  • Protein Length
  • Partial (24-478aa)
  • Protein Class
  • GPCR
  • Molecular Weight
  • 50.5 kDa
  • TMD
  • 7
  • Sequence
  • QDSRGCARWCPQDSSCVNATACRCNPG
    FSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGY
    EPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG
    FKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPG
    SPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGI
    PNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT
    IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSN
    GLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPS
    VVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS
    AFLSNNDTQNLSSPVTFTFSHRSVIPRQ

Product Description

  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • ADGRE2
  • Full Name
  • Adhesion G protein-coupled receptor E2
  • Introduction
  • This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • VBU; CD97; EMR2; CD312; CD97 antigen; EGF-like module-containing mucin-like hormone receptor-like 2; Leukocyte antigen CD97; egf-like module containing, mucin-like, hormone receptor-like 2; ADGRE2; Adhesion G protein-coupled receptor E2

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