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Magic™ Membrane Protein Human ADGRL3 (Adhesion G protein-coupled receptor L3) Expressed in CHO for Antibody Discovery, Partial (20-854) (CAT#: MPX0023K)

Datasheet
This product is a 120 kDa Human ADGRL3 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRL3
  • Protein Length
  • Partial (20-854)
  • Protein Class
  • GPCR
  • Molecular Weight
  • 120 kDa
  • TMD
  • 7
  • Sequence
  • FSRAPIPMAVVRRELSCESYPIELRCPGTDV
    IMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVV
    AGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFE
    SDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTY
    KLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYH
    DTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGT
    WDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKD
    SLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQ
    AHHGQVSYISPPIHLDSELERPSVKDISTTGPLGMGSTTTSTTLRTTTLS
    PGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTHLPSASSQIPALEESCEA
    VEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNC
    SSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVG
    LLDVQLRNLTPGGKDSAARSLNKAMVETVNNLLQPQALNAWRDLTTSDQL
    RAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDL
    KFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMK
    LGTEALSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEEN
    FNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAH
    VEVK

Product Description

  • Expression Systems
  • CHO
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 250 μg/mL in sterile PBS.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • ADGRL3
  • Full Name
  • Adhesion G protein-coupled receptor L3
  • Introduction
  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
  • Alternative Names
  • CL3; LEC3; CIRL3; LPHN3; calcium-independent alpha-latrotoxin receptor 3; latrophilin homolog 3 (cow); latrophilin-3; lectomedin 3; ADGRL3; Adhesion G protein-coupled receptor L3

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