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Magic™ Membrane Protein Human ATF6B (Activating transcription factor 6 beta) Full Length (CAT#: MPC4110K) Made to Order

Datasheet
This product is a made-to-order Human ATF6B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ATF6B
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFR
    CPEQDVPFDGSSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSL
    SSESSRLSTEPSSEALGVGEVLHVKTESLAPPLCLLGDDPTSSFETVQIN
    VIPTSDDSSDVQTKIEPVSPCSSVNSEASLLSADSSSQAFIGEEVLEVKT
    ESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTRKPPLQPKPVV
    LTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP
    RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYL
    QGLEARLQAVLADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCI
    MVFLLFIAFNFGPVSISEPPSAPISPRMNKGEPQPRRHLLGFSEQEPVQG
    VEPLQGSSQGPKEPQPSPTDQPSFSNLTAFPGGAKELLLRDLDQLFLSSD
    CRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKSQPRKKSPPVK
    AVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD
    HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVM
    DTRVIHIKTSTVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYL
    NHP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • ATF6B
  • Full Name
  • Activating transcription factor 6 beta
  • Introduction
  • The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • ATF6B; G13; CREBL1; CREB-RP; cyclic AMP-dependent transcription factor ATF-6 beta; Creb-related protein; cAMP response element-binding protein-related protein; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; protein G13; Activating transcription factor 6 beta

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