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Magic™ Membrane Protein Human BTC (Betacellulin) Expressed in E.coli for Antibody Discovery, Partial (32-111aa) (CAT#: MPX0602K)

Datasheet
This product is a 9 kDa Human BTC membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BTC
  • Protein Length
  • Partial (32-111aa)
  • Protein Class
  • Growth factor
  • Molecular Weight
  • 9 kDa
  • TMD
  • 1
  • Sequence
  • DGNSTRSPETNGLLCGDPE
    ENCAATTTQSKRKGHFSRCPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYI
    GARCERVDLFY

Product Description

  • Activity
  • Yes
  • Expression Systems
  • E.coli
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS.

Target

  • Target Protein
  • BTC
  • Full Name
  • Betacellulin
  • Introduction
  • This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
  • Alternative Names
  • BTC; probetacellulin; Betacellulin

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