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Magic™ Membrane Protein Human BTC (Betacellulin) Expressed in Yeast with 6xHis tag at the N-terminus for Antibody Discovery, Partial (32-178aa) (CAT#: MPX4347K)

Datasheet
This product is a 18.6kDa Human BTC membrane protein expressed in Yeast. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BTC
  • Protein Length
  • Partial (32-178aa)
  • Protein Class
  • Growth factor
  • Molecular Weight
  • 18.6kDa
  • TMD
  • 1
  • Sequence
  • DGNSTRSPETNGLLCGDPEENCAATTTQSKRKGHFSRCPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYIGARCERVDLFYLRGDRGQILVICLIAVMVVFIILVIGVCTCCHPLRKRRKRKKKEEEMETLGKDITPINEDIEETNIA

Product Description

  • Expression Systems
  • Yeast
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • BTC
  • Full Name
  • Betacellulin
  • Introduction
  • This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
  • Alternative Names
  • BTC; probetacellulin; Betacellulin

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