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Magic™ Membrane Protein Human CAV1 (Caveolin 1) Full Length (CAT#: MPC0456K) Made to Order

Datasheet
This product is a 20.4 kDa Human CAV1 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CAV1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 20.4 kDa
  • TMD
  • 1
  • Sequence
  • MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEID
    LVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFY
    RLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSI
    YVHTVCDPLFEAVGKIFSNVRINLQKEI

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CAV1
  • Full Name
  • Caveolin 1
  • Introduction
  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
  • Alternative Names
  • CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; caveolin-1; caveolin 1, caveolae protein, 22kDa; cell growth-inhibiting protein 32; CAV1; Caveolin 1

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