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Magic™ Membrane Protein Human CCR6 (C-C motif chemokine receptor 6) for Antibody Discovery (CAT#: MP0172X)

This product is a 42.5 kDa Human CCR6 membrane protein expressed in in vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCR6
  • Protein Length
  • Full-length
  • Molecular Weight
  • 42.5 kDa
  • TMD
  • 7
  • Sequence
  • MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM

Product Description

  • Application
  • Antibody Production
  • Expression Systems
  • in vitro wheat germ expression system with proprietary liposome technology
  • Tag
  • NO
  • Purification
  • None
  • Buffer
  • 25 mM Tris-HCl of pH8.0 containing 2% glycerol

Target

  • Target Protein
  • CCR6
  • Full Name
  • C-C motif chemokine receptor 6
  • Introduction
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene
  • Alternative Names
  • BN-1; CD196; CKR-L3; CKR6; CKRL3; CMKBR6; DCR2; DRY-6; GPR-CY4; GPR29; GPRCY4; STRL22; G protein-coupled receptor 29; OTTHUMP00000017618; OTTHUMP00000017619; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor; lymphocyte, 22; G protein-coupled receptor 29; OTTHUMP00000017618; OTTHUMP00000017619; chemokine (C-C) receptor 6; chemokine receptor-like 3; seven-transmembrane receptor, lymphocyte, 22

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