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Magic™ Membrane Protein Human CCR9 (C-C motif chemokine receptor 9) Full Length (CAT#: MPC0056K) Made to Order

This product is a 42 kDa Human CCR9 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCR9
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 42 kDa
  • TMD
  • 7
  • Sequence
  • MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHF
    LPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVT
    LPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQ
    AMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTM
    VYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKH
    KALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
    VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRRE
    GSLKLSSMLLETTSGALSL

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • 10xHis tag at C-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CCR9
  • Full Name
  • C-C motif chemokine receptor 9
  • Introduction
  • The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • GPR28; CDw199; GPR-9-6; CC-CKR-9; C-C chemokine receptor type 9; G protein-coupled receptor 28; chemokine (C-C motif) receptor 9; CCR9; C-C motif chemokine receptor 9

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