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Magic™ Membrane Protein Human CD1D (CD1d molecule) Expressed in E.coli with 6xHis and SUMO tag at the N-terminus for Antibody Discovery, Partial (20-301aa) (CAT#: MPX4555K)

Datasheet
This product is a 47.9kDa Human CD1D membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD1D
  • Protein Length
  • Partial (20-301aa)
  • Protein Class
  • Immunity
  • Molecular Weight
  • 47.9kDa
  • TMD
  • 1
  • Sequence
  • EVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • CD1D
  • Full Name
  • CD1d molecule
  • Introduction
  • This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD1D; R3; CD1A; R3G1; antigen-presenting glycoprotein CD1d; CD1D antigen, d polypeptide; HMC class I antigen-like glycoprotein CD1D; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; thymocyte antigen CD1D; CD1d molecule

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