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Magic™ Membrane Protein Human CD80 (CD80 molecule) Expressed in HEK293 for Antibody Discovery, Partial (35-242aa) (CAT#: MPX0547K)

Datasheet
This product is a 25 kDa Human CD80 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD80
  • Protein Length
  • Partial (35-242aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 25 kDa
  • TMD
  • 1
  • Sequence
  • VIHVTKEVKEVATLSC
    GHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLS
    IVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDF
    EIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAV
    SSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDN

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CD80
  • Full Name
  • CD80 molecule
  • Introduction
  • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
  • Alternative Names
  • CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; T-lymphocyte activation antigen CD80; B-lymphocyte activation antigen B7; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CTLA-4 counter-receptor B7.1; activation B7-1 antigen; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CD80 molecule

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