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Magic™ Membrane Protein Human CD99 (CD99 molecule (Xg blood group)) Expressed in NS0 for Antibody Discovery, Partial (23-122aa) (CAT#: MPX0475K)

Datasheet
This product is a 36.7 kDa Human CD99 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD99
  • Protein Length
  • Partial (23-122aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 36.7 kDa
  • TMD
  • 1
  • Sequence
  • DGGFDLSDALPDNENKKPTAIPKKPSAG
    DDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVS
    GGEGKGGSDGGGSHRKEGEEAD

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CD99
  • Full Name
  • CD99 molecule (Xg blood group)
  • Introduction
  • The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus.
  • Alternative Names
  • CD99; MIC2; HBA71; MIC2X; MIC2Y; MSK5X; CD99 antigen; E2 antigen; MIC2 (monoclonal antibody 12E7); T-cell surface glycoprotein E2; antigen identified by monoclonal 12E7, Y homolog; antigen identified by monoclonal antibodies 12E7, F21 and O13; cell surface antigen 12E7; cell surface antigen HBA-71; cell surface antigen O13; surface antigen MIC2; CD99 molecule (Xg blood group)

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