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Magic™ Membrane Protein Human CDH15 (Cadherin 15) Expressed in NS0 for Antibody Discovery, Partial (22-606aa) (CAT#: MPX0293K)

Datasheet
This product is a 90.5 kDa Human CDH15 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH15
  • Protein Length
  • Partial (22-606aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 90.5 kDa
  • TMD
  • 1
  • Sequence
  • VPGWRRPTTLYPWRRAPALSRVRRAWVIP
    PISVSENHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSIDKF
    TGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRP
    AFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPE
    LFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIITL
    DDINDNAPEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTI
    LEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQNEAPLQA
    AALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGTLVATFSAR
    DPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYR
    AIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPG
    LLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQV
    PEGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGT
    GLSLGA

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in MES, NaCl and CaCl2.

Target

  • Target Protein
  • CDH15
  • Full Name
  • Cadherin 15
  • Introduction
  • This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
  • Alternative Names
  • CDH15; CDH3; CDHM; MCAD; MRD3; CDH14; cadherin-15; cadherin 15, type 1, M-cadherin (myotubule); cadherin-14; cadherin-3; muscle-cadherin; Cadherin 15

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