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Magic™ Membrane Protein Human CDH23 (Cadherin related 23) Full Length (CAT#: MPC3591K) Made to Order

This product is a made-to-order Human CDH23 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH23
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGS
    SVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSE
    FTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTP
    IFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYETTQA
    YQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSP
    PGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLD
    RENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNS
    SEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFII
    SPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITL
    INENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFS
    DDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRIN
    VLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSI
    VSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPP
    LNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDR
    SREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVD
    GGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTV
    VAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEA
    ELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVL
    EGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTT
    TELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVY
    NVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDA
    VVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRP
    IFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNF
    RIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVED
    INDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILS
    GAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVY
    ITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRF
    NAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDS
    TVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGS
    NGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVAS
    DRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQV
    RATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFY
    HLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTL
    NTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDY
    EISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEG
    PFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGV
    LRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPV
    LLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFF
    INATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLS
    DENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTY
    QLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLN
    STAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGL
    NGELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRG
    TVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAID
    HDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNREL
    VATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITY
    YMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSS
    AGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNP
    IFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAI
    NPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVL
    DVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEG
    PGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGTTMLLVE
    VIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRY
    SFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPV
    PYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNV
    TGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFS
    FIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAE
    YTAGVATDAKVGSELIQVLALDADIGNNSLVFYSILAIHYFRALANDSED
    VGQVFTMGSMDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYI
    LRDDQRVKIVINEIPDRVRGFEEEFIHLLSNITGAIVNTDNVQFHVDKKG
    RVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDV
    QPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKA
    IVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHED
    DLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAK
    LGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIQT
    ELDEEPGDHSPGQGSLRFRHKPPVELKGPDGIHVVHGSTGTLLATDLNSL
    PEEDQKGLGRSLETLTAAEATAFERNARTESAKSTPLHKLRDVIMETPLE
    ITEL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CDH23
  • Full Name
  • Cadherin related 23
  • Introduction
  • This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
  • Alternative Names
  • CDH23; PITA5; USH1D; CDHR23; cadherin-23; cadherin-like 23; cadherin-related family member 23; otocadherin; Cadherin related 23

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