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Magic™ Membrane Protein Human COLEC12 (Collectin subfamily member 12) Expressed in NS0 for Antibody Discovery, Partial (57-742aa) (CAT#: MPX0256K)

Datasheet
This product is a 76 kDa Human COLEC12 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • COLEC12
  • Protein Length
  • Partial (57-742aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 76 kDa
  • TMD
  • 1
  • Sequence
  • LGYKVVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKK
    AISTNSELSTFRSDILDLRQQLREITEKTSKNKDTLEKLQASGDALVDRQ
    SQLKETLENNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHN
    VVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQ
    AKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI
    TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNI
    SYTAHHLRTLTSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLR
    MQQDLMRSRLDTEVANLSVIMEEMKLVDSKHGQLIKNFTILQGPPGPRGP
    RGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG
    SKGSQGPKGSRGSPGKPGPQGSSGDPGPPGPPGKEGLPGPQGPPGFQGLQ
    GTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP
    APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREE
    QQWIKKQMVGRESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGH
    GHGPGEDCAGLIYAGQWNDFQCEDVNNFICEKDRETVLSSAL

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 9xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • COLEC12
  • Full Name
  • Collectin subfamily member 12
  • Introduction
  • This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
  • Alternative Names
  • COLEC12; CLP1; NSR2; SRCL; SCARA4; collectin-12; collectin placenta protein 1; collectin sub-family member 12; hCL-P1; nurse cell scavenger receptor 2; scavenger receptor class A, member 4; scavenger receptor with C-type lectin; Collectin subfamily member 12

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