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Magic™ Membrane Protein Human CXCL10 (C-X-C motif chemokine ligand 10) for Antibody Discovery (CAT#: MP0722J)

Datasheet
This product is a 8.6 kDa Human CXCL10 membrane protein expressed in HEK293T. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CXCL10
  • Protein Length
  • Full-length
  • Protein Class
  • Druggable Genome, Secreted Protein, Transmembrane
  • Molecular Weight
  • 8.6 kDa
  • Sequence
  • MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKG
    EKRCLNPESKAIKNLLKAVSKERSKRSP

Product Description

  • Expression Systems
  • HEK293T
  • Tag
  • C-Myc/DDK
  • Purification
  • Anti-DDK affinity column followed by conventional chromatography steps
  • Purity
  • > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Buffer
  • 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Target

  • Target Protein
  • CXCL10
  • Full Name
  • C-X-C motif chemokine ligand 10
  • Introduction
  • This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection.
  • Alternative Names
  • C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10

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