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Magic™ Membrane Protein Human CXCR3 (C-X-C motif chemokine receptor 3) Full Length (CAT#: MPC0073K) Made to Order

Datasheet
This product is a 40.6 kDa Human CXCR3 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CXCR3
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 40.6 kDa
  • TMD
  • 7
  • Sequence
  • MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLN
    FDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADT
    LLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRY
    LNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNA
    THCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVSRGQRR
    LRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
    SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSS
    SRRDSSWSETSEASYSGL

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CXCR3
  • Full Name
  • C-X-C motif chemokine receptor 3
  • Introduction
  • This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4.
  • Alternative Names
  • GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; C-X-C chemokine receptor type 3; G protein-coupled receptor 9; IP-10 receptor; Mig receptor; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; interferon-inducible protein 10 receptor; CXCR3; C-X-C motif chemokine receptor 3

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