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Magic™ Membrane Protein Human DEGS1 (Delta 4-desaturase, sphingolipid 1) for Antibody Discovery (CAT#: MP0296X)

Datasheet
This product is a 64.3 kDa Human DEGS1 membrane protein expressed in in vitro wheat germ expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DEGS1
  • Protein Length
  • Full-length
  • Molecular Weight
  • 64.3 kDa
  • TMD
  • 6
  • Sequence
  • MGSRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNCKAMWNRWFGMFANLPIGIPYSISFKRYHMDHHRYLGADGVDVDIPTDFEGWFFCTAFRKFIWVILQPLFYAFRPLFINPKPITYLEVINTVAQVTFDILIYYFLGIKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLVRKIAAEYYDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE

Product Description

  • Application
  • Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array
  • Expression Systems
  • in vitro wheat germ expression system
  • Tag
  • GST-tag at N-terminal
  • Purification
  • Glutathione Sepharose 4 Fast Flow
  • Buffer
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer

Target

  • Target Protein
  • DEGS1
  • Full Name
  • Delta 4-desaturase, sphingolipid 1
  • Introduction
  • This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor
  • Alternative Names
  • DEGS; DES1; Des-1; FADS7; MGC5079; MIG15; MLD; OTTHUMP00000035598; degenerative spermatocyte homolog 1; lipid desaturase; degenerative spermatocyte homolog; lipid desaturase, dihydroceramide desaturase; membrane fatty acid (lipid) desaturase; migration-inducing gene 15 protein; sphingolipid delta 4 desatura

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