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Magic™ Membrane Protein Human DSC2 (Desmocollin 2) Full Length (CAT#: MPC2893K) Made to Order

This product is a made-to-order Human DSC2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DSC2
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVG
    RVNLKECFTAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSN
    TENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLG
    PFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRP
    VDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTF
    TIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT
    TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVND
    HLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNE
    NGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPR
    SAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPET
    RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL
    ASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD
    EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPI
    TVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAI
    LLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKV
    YSANGFTTQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQTSESCRGA
    GHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHA
    QDYVLTYNYEGRGSVAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEACMK
    R

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • DSC2
  • Full Name
  • Desmocollin 2
  • Introduction
  • This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • DSC2; DG2; DSC3; CDHF2; ARVD11; DGII/III; desmocollin-2; cadherin family member 2; desmosomal glycoprotein II/III; Desmocollin 2

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