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Magic™ Membrane Protein Human DSG4 (Desmoglein 4) Expressed in HEK293 for Antibody Discovery, Partial (24-631aa) (CAT#: MPX0502K)

Datasheet
This product is a 94 kDa Human DSG4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DSG4
  • Protein Length
  • Partial (24-631aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 94 kDa
  • TMD
  • 1
  • Sequence
  • EFIVEVKEFDIENGTTKWQTVRRQKRE
    WIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVF
    TINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDI
    NDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVS
    QEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLS
    SECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT
    DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIG
    VKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG
    SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSR
    EFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPE
    RRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAI
    LTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA
    AGIYTEDITGDTYGPVTEDQAGVSNVGLGPA

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • DSG4
  • Full Name
  • Desmoglein 4
  • Introduction
  • This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.
  • Alternative Names
  • DSG4; LAH; HYPT6; CDGF13; CDHF13; desmoglein-4; cadherin family member 13; Desmoglein 4

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