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Magic™ Membrane Protein Human ECE1 (Endothelin converting enzyme 1) Expressed in NS0 for Antibody Discovery, Partial (90-770aa) (CAT#: MPX0229K)

Datasheet
This product is a 79 kDa Human ECE1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ECE1
  • Protein Length
  • Partial (90-770aa)
  • Protein Class
  • Protease
  • Molecular Weight
  • 79 kDa
  • TMD
  • 1
  • Sequence
  • QYQTRSPSVCL
    SEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFS
    NLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLM
    ELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNS
    NVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAI
    RPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLP
    FLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVR
    KTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPM
    FVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAI
    YNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLR
    KAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGG
    IGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYS
    NYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGL
    TNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFS
    EHFRCPPGSPMNPPHKCEVW

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris, NaCl and ZnCl2.

Target

  • Target Protein
  • ECE1
  • Full Name
  • Endothelin converting enzyme 1
  • Introduction
  • The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
  • Alternative Names
  • ECE1; ECE; endothelin-converting enzyme 1; Endothelin converting enzyme 1

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