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Magic™ Membrane Protein Human EDNRB (Endothelin receptor type B) Expressed in vitro E.coli expression system (CAT#: MPX4697K)

This product is a Human EDNRB membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EDNRB
  • Protein Class
  • GPCR
  • TMD
  • 7

Product Description

  • Expression Systems
  • in vitro E.coli expression system

Target

  • Target Protein
  • EDNRB
  • Full Name
  • Endothelin receptor type B
  • Introduction
  • The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
  • Alternative Names
  • ETB; ET-B; ETB1; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2; Hirschsprung disease 2; endothelin receptor non-selective type; endothelin receptor subtype B1; EDNRB; Endothelin receptor type B

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