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Magic™ Membrane Protein Human FUT8 (Fucosyltransferase 8) Expressed in CHO for Antibody Discovery, Partial (32-575aa) (CAT#: MPX0630K)

Datasheet
This product is a 64 kDa Human FUT8 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FUT8
  • Protein Length
  • Partial (32-575aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 64 kDa
  • TMD
  • 1
  • Sequence
  • DNDHPDHSSRELSKILAKL
    ERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENY
    KKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHAD
    EFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQN
    PKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRY
    ATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPR
    PPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEAT
    KKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVD
    KKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGV
    ILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFG
    GQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRT
    GLYPSYKVREKIETVKYPTYPEAEK

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol.

Target

  • Target Protein
  • FUT8
  • Full Name
  • Fucosyltransferase 8
  • Introduction
  • This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • FUT8; CDGF; CDGF1; alpha-(1,6)-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; alpha1-6FucT; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); glycoprotein 6-alpha-L-fucosyltransferase; Fucosyltransferase 8

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