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Magic™ Membrane Protein Human GALNT12 (Polypeptide N-acetylgalactosaminyltransferase 12) Expressed in CHO for Antibody Discovery, Partial (38-581aa) (CAT#: MPX0818K)

Datasheet
This product is a 64 kDa Human GALNT12 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GALNT12
  • Protein Length
  • Partial (38-581aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 64 kDa
  • TMD
  • 1
  • Sequence
  • RAQRGAGAGAAEP
    GPPRTPRPGRREPVMPRPPVPANALGARGEAVRLQLQGEELRLQEESVRL
    HQINIYLSDRISLHRRLPERWNPLCKEKKYDYDNLPRTSVIIAFYNEAWS
    TLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSGLPKVRLI
    RANKREGLVRARLLGASAARGDVLTFLDCHCECHEGWLEPLLQRIHEEES
    AVVCPVIDVIDWNTFEYLGNSGEPQIGGFDWRLVFTWHTVPERERIRMQS
    PVDVIRSPTMAGGLFAVSKKYFEYLGSYDTGMEVWGGENLEFSFRIWQCG
    GVLETHPCSHVGHVFPKQAPYSRNKALANSVRAAEVWMDEFKELYYHRNP
    RARLEPFGDVTERKQLRDKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQ
    NKGLTDYCFDYNPPDENQIVGHQVILYLCHGMGQNQFFEYTSQKEIRYNT
    HQPEGCIAVEAGMDTLIMHLCEETAPENQKFILQEDGSLFHEQSKKCVQA
    ARKESSDSFVPLLRDCTNSDHQKWFFKERML

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • GALNT12
  • Full Name
  • Polypeptide N-acetylgalactosaminyltransferase 12
  • Introduction
  • This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.
  • Alternative Names
  • GALNT12; CRCS1; GalNAc-T12; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12); colorectal cancer, susceptibility to 1; polypeptide GalNAc transferase 12; pp-GaNTase 12; protein-UDP acetylgalactosaminyltransferase 12; Polypeptide N-acetylgalactosaminyltransferase 12

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