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Magic™ Membrane Protein Human GHSR (Growth hormone secretagogue receptor) Full Length (CAT#: MPC0327K) Made to Order

Datasheet
This product is a 41.3 kDa Human GHSR membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GHSR
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 41.3 kDa
  • TMD
  • 7
  • Sequence
  • MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATC
    VALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDL
    VRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLR
    AKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRP
    TEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVG
    ASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
    SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLST
    LKDESSRAWTESSINT

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag tag at N-terminal and 8xHis tag at C-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GHSR
  • Full Name
  • Growth hormone secretagogue receptor
  • Introduction
  • This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
  • Alternative Names
  • GHDP; growth hormone secretagogue receptor type 1; GH-releasing peptide receptor; GHRP; GHS-R; ghrelin receptor; GHSR; Growth hormone secretagogue receptor

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