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Magic™ Membrane Protein Human GLP1R, His tag (CAT#: MP1484F)

This product is recombinant Human GLP1R membrane protein. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GLP1R
  • Protein Length
  • Full Length
  • Protein Class
  • GPCR
  • TMD
  • 7

Product Description

  • Tag
  • His tag

Target

  • Target Protein
  • GLP1R
  • Full Name
  • Glucagon like peptide 1 receptor
  • Introduction
  • This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
  • Alternative Names
  • GLP-1; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; GLP-1 receptor; GLP1 receptor; seven transmembrane helix receptor

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