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Magic™ Membrane Protein Human HLA-DOA (Major histocompatibility complex, class II, DO alpha) Full Length (CAT#: MPC4102K) Made to Order

This product is a made-to-order Human HLA-DOA membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HLA-DOA
  • Protein Length
  • Full length
  • Protein Class
  • Immunity
  • TMD
  • 1
  • Sequence
  • MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTH
    EFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILV
    ERSNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRN
    GQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPL
    LRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • HLA-DOA
  • Full Name
  • Major histocompatibility complex, class II, DO alpha
  • Introduction
  • HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
  • Alternative Names
  • HLA-DOA; HLADZ; HLA-DNA; HLA-DZA; HLA class II histocompatibility antigen, DO alpha chain; HLA-D0-alpha; MHC DN-alpha; MHC DZ alpha; MHC class II antigen DOA; lymphocyte antigen; major histocompatibility complex, class II, DN alpha; Major histocompatibility complex, class II, DO alpha

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