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Magic™ Membrane Protein Human HLA-DQA2 (Major histocompatibility complex, class II, DQ alpha 2) Full Length (CAT#: MPC4074K) Made to Order

Datasheet
This product is a made-to-order Human HLA-DQA2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HLA-DQA2
  • Protein Length
  • Full length
  • Protein Class
  • Immunity
  • TMD
  • 1
  • Sequence
  • MILNKALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTH
    EFDGDEEFYVDLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMM
    RQSNSTAATNEVPEVTVFSKFPVTLGQPNTLICLVDNIFPPVVNITWLSN
    GHSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPL
    LKHWEPEIPAPMSELTETLVCALGLSVGLMGIVVGTVFIIQGLRSVGASR
    HQGLL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • HLA-DQA2
  • Full Name
  • Major histocompatibility complex, class II, DQ alpha 2
  • Introduction
  • This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
  • Alternative Names
  • HLA-DQA2; HLA-DCA; HLA-DXA; HLADQA2; DC-alpha; DX-ALPHA; HLA class II histocompatibility antigen, DQ alpha 2 chain; DC-1 alpha chain; DX alpha chain; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; MHC class II DQA1; MHC class II DQA2; MHC class II antigen; Major histocompatibility complex, class II, DQ alpha 2

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