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Magic™ Membrane Protein Human ICAM3 (Intercellular adhesion molecule 3) Expressed in NS0 for Antibody Discovery, Partial (30-485aa) (CAT#: MPX0505K)

Datasheet
This product is a 76.7 kDa Human ICAM3 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICAM3
  • Protein Length
  • Partial (30-485aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 76.7 kDa
  • TMD
  • 1
  • Sequence
  • QEFLLRVEPQNPVLSAGGSLF
    VNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYC
    NGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSL
    TVVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQG
    LGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPAS
    EAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG
    ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVP
    AAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGP
    KIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPF
    FVNVTHNGTYQCQASSSRGKYTLVVVMDIEAGSSH

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 1 mg/mL in sterile, deionized water.
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • ICAM3
  • Full Name
  • Intercellular adhesion molecule 3
  • Introduction
  • The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • ICAM3; CD50; CDW50; ICAM-R; ICAM-3; Intercellular adhesion molecule 3

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