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Magic™ Membrane Protein Human IGSF8 (Immunoglobulin superfamily member 8) Expressed in HEK293 for Antibody Discovery, Partial (28-579aa) (CAT#: MPX0403K)

Datasheet
This product is a 85 kDa Human IGSF8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IGSF8
  • Protein Length
  • Partial (28-579aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 85 kDa
  • TMD
  • 1
  • Sequence
  • REVLVPEGPLYRVAGTAVSISCN
    VTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEV
    QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLP
    DVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAV
    SFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGT
    DRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQT
    LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPA
    GAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGD
    AGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGG
    TVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGV
    GQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWV
    QHADYSWYQAGSARSGPVTVYPYMHALDT

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IGSF8
  • Full Name
  • Immunoglobulin superfamily member 8
  • Introduction
  • This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
  • Alternative Names
  • IGSF8; EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1; CD81 partner 3; glu-Trp-Ile EWI motif-containing protein 2; keratinocytes-associated transmembrane protein 4; prostaglandin regulatory-like protein; Immunoglobulin superfamily member 8

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